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Conformational flexibility and binding interactions of the G protein βγ heterodimer

Previous NMR experiments on unbound G protein βγ heterodimer suggested that particular residues in the binding interface are mobile on the nanosecond timescale. In this work we performed nanosecond-timescale molecular dynamics simulations to investigate conformational changes and dynamics of Gβγ in...

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Detalhes bibliográficos
Main Authors: Park, Min-Sun, Smrcka, Alan V., Stern, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974715/
https://ncbi.nlm.nih.gov/pubmed/21064128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22899
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