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Understanding Molecular Recognition by G protein βγ Subunits on the Path to Pharmacological Targeting
Heterotrimeric G proteins, composed of Gα and Gβγ subunits, transduce extracellular signals via G-protein-coupled receptors to modulate many important intracellular responses. The Gβγ subunits hold a central position in this signaling system and have been implicated in multiple aspects of physiology...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187535/ https://ncbi.nlm.nih.gov/pubmed/21737569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.073072 |
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