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Understanding Molecular Recognition by G protein βγ Subunits on the Path to Pharmacological Targeting

Heterotrimeric G proteins, composed of Gα and Gβγ subunits, transduce extracellular signals via G-protein-coupled receptors to modulate many important intracellular responses. The Gβγ subunits hold a central position in this signaling system and have been implicated in multiple aspects of physiology...

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Detalhes bibliográficos
Main Authors: Lin, Yuan, Smrcka, Alan V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187535/
https://ncbi.nlm.nih.gov/pubmed/21737569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.073072
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