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Evaluating Docking Methods for Prediction of Binding Affinities of Small Molecules to the G Protein βγ Subunits

Several studies have suggested that disrupting interactions of the G protein βγ subunits with downstream binding partners might be a valuable study for pharmaceutical development. Recently, small molecules have been found which bind to Gβγ with high apparent affinity in an enzyme-linked immunosorben...

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Autori principali: Park, Min-Sun, Dessal, Axel L., Smrcka, Alan V., Stern, Harry A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846521/
https://ncbi.nlm.nih.gov/pubmed/19434844
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