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Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor

Fanconi Anemia (FA) is a rare disease characterized by congenital defects, progressive bone marrow failure and heightened cancer susceptibility. The FA proteins, BRCA1, and FANCD1/BRCA2, function cooperatively in the FA-BRCA pathway, to repair damaged DNA. Activation of the FA-BRCA pathway occurs vi...

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Autors principals: Rego, MA, Harney, JA, Mauro, M, Shen, M, Howlett, NG
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974337/
https://ncbi.nlm.nih.gov/pubmed/21685936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.237
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