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Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor
Fanconi Anemia (FA) is a rare disease characterized by congenital defects, progressive bone marrow failure and heightened cancer susceptibility. The FA proteins, BRCA1, and FANCD1/BRCA2, function cooperatively in the FA-BRCA pathway, to repair damaged DNA. Activation of the FA-BRCA pathway occurs vi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974337/ https://ncbi.nlm.nih.gov/pubmed/21685936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.237 |
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