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Photocleavable fluorescent nucleotides for DNA sequencing on a chip constructed by site-specific coupling chemistry
DNA sequencing by synthesis on a solid surface offers new paradigms to overcome limitations of electrophoresis-based sequencing methods. Here we report DNA sequencing by synthesis using photocleavable (PC) fluorescent nucleotides [dUTP-PC-4,4-difluoro-4-bora-3α,4α-diaza-s-indacene (Bodipy)-FL-510, d...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2004
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15064393/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401138101 |
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