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Photocleavage of a 2-nitrobenzyl linker bridging a fluorophore to the 5′ end of DNA

Three single-stranded DNA molecules of different lengths were synthesized and characterized, each containing a fluorescent dye (6-carboxyfluorescein) connected to the 5′ end via a photocleavable 2-nitrobenzyl linker and a biotin moiety at the 3′ end. UV irradiation (λ ≈ 340 nm) of solutions containi...

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Detalhes bibliográficos
Main Authors: Bai, Xiaopeng, Li, Zengmin, Jockusch, Steffen, Turro, Nicholas J., Ju, Jingyue
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141008/
https://ncbi.nlm.nih.gov/pubmed/12515854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242729099
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