Epidermal or Dermal Specific Knockout of PHD-2 Enhances Wound Healing and Minimizes Ischemic Injury

INTRODUCTION: Hypoxia-inducible factor (HIF)-1α, part of the heterodimeric transcription factor that mediates the cellular response to hypoxia, is critical for the expression of multiple angiogenic growth factors, cell motility, and the recruitment of endothelial progenitor cells. Inhibition of the...

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Detalhes bibliográficos
Main Authors: Zimmermann, Andrew S., Morrison, Shane D., Hu, Michael S., Li, Shuli, Nauta, Allison, Sorkin, Michael, Meyer, Nathaniel P., Walmsley, Graham G., Maan, Zeshaan N., Chan, Denise A., Gurtner, Geoffrey C., Giaccia, Amato J., Longaker, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973687/
https://ncbi.nlm.nih.gov/pubmed/24695462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093373
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