PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing

BACKGROUND: Cell therapy with mesenchymal stromal cells is a promising strategy for tissue repair. Restoration of blood flow to ischemic tissues is a key step in wound repair, and MSCs have been shown to be proangiogenic. Angiogenesis is critically regulated by the hypoxia-inducible factor (HIF) sup...

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Pubblicato in:Plast Reconstr Surg
Autori principali: Ko, Sae Hee, Nauta, Allison C., Morrison, Shane D., Hu, Michael S., Zimmermann, Andrew S., Chung, Michael T., Glotzbach, Jason P., Wong, Victor W., Walmsley, Graham G., Lorenz, H. Peter, Chan, Denise A., Gurtner, Geoffrey C., Giaccia, Amato J., Longaker, Michael T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747314/
https://ncbi.nlm.nih.gov/pubmed/29280872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0000000000003959
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