PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing

BACKGROUND: Cell therapy with mesenchymal stromal cells is a promising strategy for tissue repair. Restoration of blood flow to ischemic tissues is a key step in wound repair, and MSCs have been shown to be proangiogenic. Angiogenesis is critically regulated by the hypoxia-inducible factor (HIF) sup...

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Publicado no:Plast Reconstr Surg
Main Authors: Ko, Sae Hee, Nauta, Allison C., Morrison, Shane D., Hu, Michael S., Zimmermann, Andrew S., Chung, Michael T., Glotzbach, Jason P., Wong, Victor W., Walmsley, Graham G., Lorenz, H. Peter, Chan, Denise A., Gurtner, Geoffrey C., Giaccia, Amato J., Longaker, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747314/
https://ncbi.nlm.nih.gov/pubmed/29280872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0000000000003959
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