PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing

BACKGROUND: Cell therapy with mesenchymal stromal cells is a promising strategy for tissue repair. Restoration of blood flow to ischemic tissues is a key step in wound repair, and MSCs have been shown to be proangiogenic. Angiogenesis is critically regulated by the hypoxia-inducible factor (HIF) sup...

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Vydáno v:Plast Reconstr Surg
Hlavní autoři: Ko, Sae Hee, Nauta, Allison C., Morrison, Shane D., Hu, Michael S., Zimmermann, Andrew S., Chung, Michael T., Glotzbach, Jason P., Wong, Victor W., Walmsley, Graham G., Lorenz, H. Peter, Chan, Denise A., Gurtner, Geoffrey C., Giaccia, Amato J., Longaker, Michael T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747314/
https://ncbi.nlm.nih.gov/pubmed/29280872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0000000000003959
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