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Comparison of the Hydroxylase Inhibitor DMOG and the Iron Chelator Deferoxamine in Diabetic and Aged Wound Healing

A hallmark of diabetes mellitus is the breakdown of almost every reparative process in the human body leading to critical impairments of wound healing. Stabilization and activity of the transcription factor HIF-1α is impaired in diabetes, leading to deficits in new blood vessel formation in response...

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Dettagli Bibliografici
Pubblicato in:Plast Reconstr Surg
Autori principali: Duscher, Dominik, Januszyk, Michael, Maan, Zeshaan N., Whittam, Alexander J., Hu, Michael S., Walmsley, Graham G., Dong, Yixiao, Khong, Sacha M., Longaker, Michael T., Gurtner, Geoffrey C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327844/
https://ncbi.nlm.nih.gov/pubmed/28234841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0000000000003072
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