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Strong antitumor activities of IgG3 antibodies to a human melanoma-associated ganglioside.
Three mouse monoclonal IgG3 antibodies, 2B2, IF4, and MG-21, recognize a GD3 ganglioside antigen that is expressed at the cell surface of most human melanomas. All three antibodies mediate antibody-dependent cellular cytotoxicity (ADCC) in vitro when tested with human lymphocytes as effector cells i...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1985
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397290/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3856277/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.5.1499 |
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