Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma.

R24 is an IgG3 mouse monoclonal antibody that identifies GD3, a prominent ganglioside on the surface of melanoma cells and other cells of neuroectodermal origin. Twelve patients with metastatic melanoma were treated with R24 at three dose levels, 8, 80, or 240 mg/m2, over a period of 2 weeks. Peak a...

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Библиографические подробности
Главные авторы: Houghton, A N, Mintzer, D, Cordon-Cardo, C, Welt, S, Fliegel, B, Vadhan, S, Carswell, E, Melamed, M R, Oettgen, H F, Old, L J
Формат: Artigo
Язык:Inglês
Опубликовано: 1985
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC397231/
https://ncbi.nlm.nih.gov/pubmed/3883355
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