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Strong antitumor activities of IgG3 antibodies to a human melanoma-associated ganglioside.

Three mouse monoclonal IgG3 antibodies, 2B2, IF4, and MG-21, recognize a GD3 ganglioside antigen that is expressed at the cell surface of most human melanomas. All three antibodies mediate antibody-dependent cellular cytotoxicity (ADCC) in vitro when tested with human lymphocytes as effector cells i...

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Bibliografiske detaljer
Main Authors: Hellström, I, Brankovan, V, Hellström, K E
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC397290/
https://ncbi.nlm.nih.gov/pubmed/3856277
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