Strong antitumor activities of IgG3 antibodies to a human melanoma-associated ganglioside.

Three mouse monoclonal IgG3 antibodies, 2B2, IF4, and MG-21, recognize a GD3 ganglioside antigen that is expressed at the cell surface of most human melanomas. All three antibodies mediate antibody-dependent cellular cytotoxicity (ADCC) in vitro when tested with human lymphocytes as effector cells i...

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Detalles Bibliográficos
Autores principales: Hellström, I, Brankovan, V, Hellström, K E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC397290/
https://ncbi.nlm.nih.gov/pubmed/3856277
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