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RanBP9 overexpression reduces dendritic arbor and spine density

RanBP9 is a multi-domain scaffolding protein known to integrate extracellular signaling with intracellular targets. We previously demonstrated that RanBP9 enhances Aβ generation and amyloid plaque burden which results in loss of specific pre- and postsynaptic proteins in vivo in a transgenic mouse m...

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Bibliographic Details
Main Authors: Wang, Hongjie, Lewsadder, Meagan, Dorn, Eric, Xu, Shaohua, Lakshmana, Madepalli K.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972333/
https://ncbi.nlm.nih.gov/pubmed/24486966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.01.045
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