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TREM2 and the neuroimmunology of Alzheimer’s disease

Late-onset Alzheimer’s disease (AD) is a sporadic disorder with increasing prevalence in aging. The ε4 allele of Apolipoprotein E(ApoEε4) was the only known major risk factor for late onset AD. Recently, two groups of investigators independently identified variants of the TREM2 gene, encoding trigge...

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Autori principali: Hickman, Suzanne E., Khoury, Joseph El
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972304/
https://ncbi.nlm.nih.gov/pubmed/24355566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.11.021
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