TREM2 Variants in Alzheimer's Disease

BACKGROUND: Homozygous loss-of-function mutations in TREM2, encoding the triggering receptor expressed on myeloid cells 2 protein, have previously been associated with an autosomal recessive form of early-onset dementia. METHODS: We used genome, exome, and Sanger sequencing to analyze the genetic va...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Guerreiro, Rita, Wojtas, Aleksandra, Bras, Jose, Carrasquillo, Minerva, Rogaeva, Ekaterina, Majounie, Elisa, Cruchaga, Carlos, Sassi, Celeste, Kauwe, John S.K., Younkin, Steven, Hazrati, Lilinaz, Collinge, John, Pocock, Jennifer, Lashley, Tammaryn, Williams, Julie, Lambert, Jean-Charles, Amouyel, Philippe, Goate, Alison, Rademakers, Rosa, Morgan, Kevin, Powell, John, St. George-Hyslop, Peter, Singleton, Andrew, Hardy, John
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631573/
https://ncbi.nlm.nih.gov/pubmed/23150934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1211851
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares