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TREM2 is associated with increased risk for Alzheimer’s disease in African Americans

BACKGROUND: TREM2 encodes for triggering receptor expressed on myeloid cells 2 and has rare, coding variants that associate with risk for late-onset Alzheimer’s disease (LOAD) in Caucasians of European and North-American origin. This study evaluated the role of TREM2 in LOAD risk in African-American...

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Pubblicato in:Mol Neurodegener
Autori principali: Jin, Sheng Chih, Carrasquillo, Minerva M, Benitez, Bruno A, Skorupa, Tara, Carrell, David, Patel, Dwani, Lincoln, Sarah, Krishnan, Siddharth, Kachadoorian, Michaela, Reitz, Christiane, Mayeux, Richard, Wingo, Thomas S, Lah, James J, Levey, Allan I, Murrell, Jill, Hendrie, Hugh, Foroud, Tatiana, Graff-Radford, Neill R, Goate, Alison M, Cruchaga, Carlos, Ertekin-Taner, Nilüfer
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426167/
https://ncbi.nlm.nih.gov/pubmed/25886450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0016-9
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