Expression and processing analyses of wild type and p.R47H TREM2 variant in Alzheimer’s disease brains

BACKGROUND: Genetic analyses showed that the triggering receptor expressed in myeloid cells 2 (TREM2) p.R47H variant increases the risk for Alzheimer’s disease (AD). The question of whether the p.R47H mutation affects expression or function of the receptor remains unanswered. To address this questio...

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Bibliografiske detaljer
Udgivet i:Mol Neurodegener
Main Authors: Ma, Li, Allen, Mariet, Sakae, Nobutaka, Ertekin-Taner, Nilufer, Graff-Radford, Neill R., Dickson, Dennis W., Younkin, Steven G., Sevlever, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124229/
https://ncbi.nlm.nih.gov/pubmed/27887626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0137-9
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