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Expression and processing analyses of wild type and p.R47H TREM2 variant in Alzheimer’s disease brains
BACKGROUND: Genetic analyses showed that the triggering receptor expressed in myeloid cells 2 (TREM2) p.R47H variant increases the risk for Alzheimer’s disease (AD). The question of whether the p.R47H mutation affects expression or function of the receptor remains unanswered. To address this questio...
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Publicado no: | Mol Neurodegener |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5124229/ https://ncbi.nlm.nih.gov/pubmed/27887626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0137-9 |
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