Insights into TREM2 biology by network analysis of human brain gene expression data

Rare variants in TREM2 cause susceptibility to late-onset Alzheimer's disease. Here we use microarray-based expression data generated from 101 neuropathologically normal individuals and covering 10 brain regions, including the hippocampus, to understand TREM2 biology in human brain. Using netwo...

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Detalhes bibliográficos
Main Authors: Forabosco, Paola, Ramasamy, Adaikalavan, Trabzuni, Daniah, Walker, Robert, Smith, Colin, Bras, Jose, Levine, Adam P., Hardy, John, Pocock, Jennifer M., Guerreiro, Rita, Weale, Michael E., Ryten, Mina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988951/
https://ncbi.nlm.nih.gov/pubmed/23855984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.05.001
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