Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme CYP24A1 in multiple sclerosis()

BACKGROUND: Multiple sclerosis (MS) is a common disease of the central nervous system and a major cause of disability amongst young adults. Genome-wide association studies have identified many novel susceptibility loci including rs2248359. We hypothesized that genotypes of this locus could increase...

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Vydáno v:Mult Scler Relat Disord
Hlavní autoři: Ramasamy, Adaikalavan, Trabzuni, Daniah, Forabosco, Paola, Smith, Colin, Walker, Robert, Dillman, Allissa, Sveinbjornsdottir, Sigurlaug, Hardy, John, Weale, Michael E., Ryten, Mina
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B. V 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278441/
https://ncbi.nlm.nih.gov/pubmed/25568836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.msard.2013.08.009
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