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Investigation of pathology, expression and proteomic profiles in human TREM2 variant postmortem brains with and without Alzheimer’s disease

Triggering receptor expressed on myeloid cells 2 TREM2 was identified as a risk factor for late onset Alzheimer’s disease (AD). Here we compared TREM2 cases with a variant (TREM2(+)) and cases without a TREM2 variant (TREM2(−)), considering pathological burden, inflammatory response and altered cano...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Toomey, Christina E., Heywood, Wendy, Benson, Bridget C., Packham, Georgia, Mills, Kevin, Lashley, Tammaryn
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018003/
https://ncbi.nlm.nih.gov/pubmed/32267026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12842
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