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Investigation of pathology, expression and proteomic profiles in human TREM2 variant postmortem brains with and without Alzheimer’s disease

Triggering receptor expressed on myeloid cells 2 TREM2 was identified as a risk factor for late onset Alzheimer’s disease (AD). Here we compared TREM2 cases with a variant (TREM2(+)) and cases without a TREM2 variant (TREM2(−)), considering pathological burden, inflammatory response and altered cano...

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Bibliografische gegevens
Gepubliceerd in:Brain Pathol
Hoofdauteurs: Toomey, Christina E., Heywood, Wendy, Benson, Bridget C., Packham, Georgia, Mills, Kevin, Lashley, Tammaryn
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018003/
https://ncbi.nlm.nih.gov/pubmed/32267026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12842
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