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TREM2 and the neuroimmunology of Alzheimer’s disease

Late-onset Alzheimer’s disease (AD) is a sporadic disorder with increasing prevalence in aging. The ε4 allele of Apolipoprotein E(ApoEε4) was the only known major risk factor for late onset AD. Recently, two groups of investigators independently identified variants of the TREM2 gene, encoding trigge...

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Detalhes bibliográficos
Main Authors: Hickman, Suzanne E., Khoury, Joseph El
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972304/
https://ncbi.nlm.nih.gov/pubmed/24355566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.11.021
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