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Oxidative aliphatic C-H fluorination with manganese catalysts and fluoride ion

Fluorination is a reaction that is useful in improving the chemical stability and changing the binding affinity of biologically active compounds. The protocol described here can be used to replace aliphatic, C(sp(3))-H hydrogen in small molecules with fluorine. Notably, isolated methylene groups and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Wei, Huang, Xiongyi, Groves, John T
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972251/
https://ncbi.nlm.nih.gov/pubmed/24177292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2013.144
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