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Oxidative aliphatic C-H fluorination with manganese catalysts and fluoride ion
Fluorination is a reaction that is useful in improving the chemical stability and changing the binding affinity of biologically active compounds. The protocol described here can be used to replace aliphatic, C(sp(3))-H hydrogen in small molecules with fluorine. Notably, isolated methylene groups and...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972251/ https://ncbi.nlm.nih.gov/pubmed/24177292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2013.144 |
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