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Misfolded proteins, endoplasmic reticulum stress and neurodegeneration

The accumulation of misfolded proteins (e.g. mutant or damaged proteins) triggers cellular stress responses that protect cells against the toxic buildup of such proteins. However, prolonged stress due to the buildup of these toxic proteins induces specific death pathways. Dissecting these pathways s...

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Bibliografski detalji
Glavni autori: Rao, Rammohan V, Bredesen, Dale E
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970707/
https://ncbi.nlm.nih.gov/pubmed/15530777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2004.09.012
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