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Coupling Endoplasmic Reticulum Stress to the Cell Death Program in Dopaminergic Cells: Effect of Paraquat

Parkinson’s disease (PD) features oxidative stress and accumulation of misfolded (unfolded, alternatively folded, or mutant) proteins with associated loss of dopaminergic neurons. Oxidative stress and the accumulated misfolded proteins elicit cellular responses that include an endoplasmic reticulum...

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Detalhes bibliográficos
Main Authors: Chinta, Shankar J, Rane, Anand, Poksay, Karen S, Bredesen, Dale E, Andersen, Julie K, Rao, Rammohan V
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818083/
https://ncbi.nlm.nih.gov/pubmed/18773310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-008-8047-9
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