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Role of Calcineurin in Neurodegeneration Produced by Misfolded Proteins and Endoplasmic Reticulum Stress

A hallmark event in neurodegenerative diseases is the accumulation in the brain of misfolded aggregated proteins, leading to neuronal dysfunction and disease. Compelling evidences suggest that misfolded proteins damage cells by inducing endoplasmic reticulum stress and alterations in calcium homeost...

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Bibliografiska uppgifter
Huvudupphovsmän: Mukherjee, Abhisek, Soto, Claudio
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078182/
https://ncbi.nlm.nih.gov/pubmed/21295458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2010.12.006
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