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Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging

The misfolding, aggregation, and tissue accumulation of proteins are common events in diverse chronic diseases, known as protein misfolding disorders. Many of these diseases are associated with aging, but the mechanism for this connection is unknown. Recent evidence has shown that the formation and...

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Autors principals: Cuanalo-Contreras, Karina, Mukherjee, Abhisek, Soto, Claudio
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855986/
https://ncbi.nlm.nih.gov/pubmed/24348562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/638083
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