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Type 2 Diabetes as a Protein Misfolding Disease
Type 2 diabetes is a highly prevalent and chronic metabolic disorder. Recent evidence suggests that formation of toxic aggregates of the islet amyloid polypeptide (IAPP) might contribute to β-cell dysfunction and disease. However, the mechanism of protein aggregation and associated toxicity is still...
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| Publicado no: | Trends Mol Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492843/ https://ncbi.nlm.nih.gov/pubmed/25998900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2015.04.005 |
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