Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

Most cells in the well-known pre-B-lymphocyte line 18-81 have correctly assembled genes for both alleles at the immunoglobulin heavy chain locus. Only one allele is "active"; the other, "silent" allele contains an amber termination codon. The rate of reversion of this amber codon was determined to b...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Wabl, M, Burrows, P D, von Gabain, A, Steinberg, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3918310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.2.479
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