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High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene.

The "silent" allele at the immunoglobulin heavy-chain locus in the pre-B-lymphocyte line 18-81 contains a correctly assembled gene. However, an amber termination codon within the variable-region gene segment prematurely terminates translation into complete heavy chain. Revertants that do p...

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Detalhes bibliográficos
Main Authors: Meyer, J, Jäck, H M, Ellis, N, Wabl, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC386628/
https://ncbi.nlm.nih.gov/pubmed/3092221
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