Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.
Most cells in the well-known pre-B-lymphocyte line 18-81 have correctly assembled genes for both alleles at the immunoglobulin heavy chain locus. Only one allele is "active"; the other, "silent" allele contains an amber termination codon. The rate of reversion of this amber codon was determined to b...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1985
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3918310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.2.479 |
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