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Immunoglobulin heavy chain toxicity in plasma cells is neutralized by fusion to pre-B cells.

A plasma cell hybridoma frequently loses its immunoglobulin heavy (H) chain spontaneously but rarely is production of its light (L) chain lost. Upon fusion to a pre-B-cell hybridoma that produces no Ig chain, the L chain is frequently lost. In cells without the L chain the H chain, which is derived...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Haas, I G, Wabl, M R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6438634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.22.7185
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