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Allelic inclusion in a pre-B-cell line that generates immunoglobulin heavy chain genes in vitro.

In a pre-B-cell line that rearranges its heavy chain gene segments in vitro, we found that the rate of productive rearrangement on one allele was not influenced by the presence of heavy chain protein encoded by the other allele. This shows that allelic exclusion of heavy chain genes is not regulated...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Beck-Engeser, G, Jäck, H M, Wabl, M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3103122/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.4.1060
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