Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans

BACKGROUND & AIMS: Trefoil factors (TFFs) regulate mucosal repair and suppress tumor formation in the stomach. Tff1 deficiency results in gastric cancer, whereas Tff2 deficiency increases gastric inflammation. TFF2 expression is frequently lost in gastric neoplasms, but the nature of the silenci...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Peterson, Anthony J., Menheniott, Trevelyan R., O’Connor, Louise, Walduck, Anna K., Fox, James G., Kawakami, Kazuyuki, Minamoto, Toshinari, Ong, Eng Kok, Wang, Timothy C., Judd, Louise M., Giraud, Andrew S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970568/
https://ncbi.nlm.nih.gov/pubmed/20801119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.08.043
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia