Helicobacter pylori CagA Triggers Expression of the Bactericidal Lectin REG3γ via Gastric STAT3 Activation

BACKGROUND: Most of what is known about the Helicobacter pylori (H. pylori) cytotoxin, CagA, pertains to a much-vaunted role as a determinant of gastric inflammation and cancer. Little attention has been devoted to potential roles of CagA in the majority of H. pylori infected individuals not showing...

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Main Authors: Lee, Kai Syin, Kalantzis, Anastasia, Jackson, Cameron B., O'Connor, Louise, Murata-Kamiya, Naoko, Hatakeyama, Masanori, Judd, Louise M., Giraud, Andrew S., Menheniott, Trevelyan R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270022/
https://ncbi.nlm.nih.gov/pubmed/22312430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030786
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