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Helicobacter pylori CagA Causes Mitotic Impairment and Induces Chromosomal Instability
Infection with cagA-positive Helicobacter pylori is the strongest risk factor for the development of gastric carcinoma. The cagA gene product CagA, which is delivered into gastric epithelial cells, specifically binds to and aberrantly activates SHP-2 oncoprotein. CagA also interacts with and inhibit...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755941/ https://ncbi.nlm.nih.gov/pubmed/19546211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035766 |
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