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Helicobacter pylori CagA Causes Mitotic Impairment and Induces Chromosomal Instability

Infection with cagA-positive Helicobacter pylori is the strongest risk factor for the development of gastric carcinoma. The cagA gene product CagA, which is delivered into gastric epithelial cells, specifically binds to and aberrantly activates SHP-2 oncoprotein. CagA also interacts with and inhibit...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Umeda, Mayumi, Murata-Kamiya, Naoko, Saito, Yasuhiro, Ohba, Yusuke, Takahashi, Masayuki, Hatakeyama, Masanori
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755941/
https://ncbi.nlm.nih.gov/pubmed/19546211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035766
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