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Potentiation of Helicobacter pylori CagA Protein Virulence through Homodimerization

Chronic infection with Helicobacter pylori cagA-positive strains is associated with atrophic gastritis, peptic ulceration, and gastric carcinoma. The cagA gene product, CagA, is delivered into gastric epithelial cells via type IV secretion, where it undergoes tyrosine phosphorylation at the EPIYA mo...

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Autors principals: Nagase, Lisa, Murata-Kamiya, Naoko, Hatakeyama, Masanori
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190882/
https://ncbi.nlm.nih.gov/pubmed/21813645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.258673
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