Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA

CagA, encoded by cytotoxin-associated gene A (cagA), is a major virulence factor of Helicobacter pylori, a gastric pathogen involved in the development of upper gastrointestinal diseases. Infection with cagA-positive H. pylori may also be associated with diseases outside the stomach, although the me...

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Udgivet i:Sci Rep
Main Authors: Shimoda, Asako, Ueda, Koji, Nishiumi, Shin, Murata-Kamiya, Naoko, Mukai, Sada-atsu, Sawada, Shin-ichi, Azuma, Takeshi, Hatakeyama, Masanori, Akiyoshi, Kazunari
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703974/
https://ncbi.nlm.nih.gov/pubmed/26739388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18346
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