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Potentiation of Helicobacter pylori CagA Protein Virulence through Homodimerization
Chronic infection with Helicobacter pylori cagA-positive strains is associated with atrophic gastritis, peptic ulceration, and gastric carcinoma. The cagA gene product, CagA, is delivered into gastric epithelial cells via type IV secretion, where it undergoes tyrosine phosphorylation at the EPIYA mo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190882/ https://ncbi.nlm.nih.gov/pubmed/21813645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.258673 |
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