Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFF1 epigenetic silencing

BACKGROUND & AIMS: Epigenetic alterations have been correlated with field cancerization in human patients, but evidence from experimental models that specific epigenetic changes can initiate cancer has been lacking. Although hormones have been associated with cancer risk, the mechanisms have not...

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Hlavní autoři: Tomita, Hiroyuki, Takaishi, Shigeo, Menheniott, Trevelyan R., Yang, Xiangdong, Shibata, Wataru, Jin, Guangchun, Betz, Kelly S., Kawakami, Kazuyuki, Minamoto, Toshinari, Tomasetto, Catherine, Rio, Marie-Christine, Lerkowit, Nataporn, Varro, Andrea, Giraud, Andrew S., Wang, Timothy C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049860/
https://ncbi.nlm.nih.gov/pubmed/21111741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.11.037
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