Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFF1 epigenetic silencing

BACKGROUND & AIMS: Epigenetic alterations have been correlated with field cancerization in human patients, but evidence from experimental models that specific epigenetic changes can initiate cancer has been lacking. Although hormones have been associated with cancer risk, the mechanisms have not...

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Главные авторы: Tomita, Hiroyuki, Takaishi, Shigeo, Menheniott, Trevelyan R., Yang, Xiangdong, Shibata, Wataru, Jin, Guangchun, Betz, Kelly S., Kawakami, Kazuyuki, Minamoto, Toshinari, Tomasetto, Catherine, Rio, Marie-Christine, Lerkowit, Nataporn, Varro, Andrea, Giraud, Andrew S., Wang, Timothy C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049860/
https://ncbi.nlm.nih.gov/pubmed/21111741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.11.037
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