Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.

Induction of transformation, cell lethality, and DNA lesions were quantitatively compared in Syrian hamster embryo cells (HEC) treated with three different methylating agents: N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), N-methyl-N-nitrosourea (MNU), or methyl methanesulfonate (MMS). Each induc...

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Detaylı Bibliyografya
Asıl Yazarlar: Doniger, J, Day, R S, DiPaolo, J A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1985
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC397050/
https://ncbi.nlm.nih.gov/pubmed/3855560
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