Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.

Induction of transformation, cell lethality, and DNA lesions were quantitatively compared in Syrian hamster embryo cells (HEC) treated with three different methylating agents: N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), N-methyl-N-nitrosourea (MNU), or methyl methanesulfonate (MMS). Each induc...

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Bibliografske podrobnosti
Main Authors: Doniger, J, Day, R S, DiPaolo, J A
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC397050/
https://ncbi.nlm.nih.gov/pubmed/3855560
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