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Both base excision repair and O(6)-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis

Methylating agents are widely distributed environmental carcinogens. Moreover, they are being used in cancer chemotherapy. The primary target of methylating agents is DNA, and therefore, DNA repair is the first-line barrier in defense against their toxic and carcinogenic effects. Methylating agents...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wirtz, Stefan, Nagel, Georg, Eshkind, Leonid, Neurath, Markus F., Samson, Leona D., Kaina, Bernd
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994278/
https://ncbi.nlm.nih.gov/pubmed/20732909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq174
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