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Effect of O(6)-methylguanine-DNA methyltransferase methylation in medulloblastoma
Medulloblastoma is a highly malignant brain tumor that predominately affects children and requires multimodal treatment, including chemotherapy with alkylating agents. O(6)-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that plays an important role in tumor resistance to alkylatin...
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| 出版年: | Mol Clin Oncol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
D.A. Spandidos
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5740829/ https://ncbi.nlm.nih.gov/pubmed/29285383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2017.1431 |
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