Effect of O(6)-methylguanine-DNA methyltransferase methylation in medulloblastoma

Medulloblastoma is a highly malignant brain tumor that predominately affects children and requires multimodal treatment, including chemotherapy with alkylating agents. O(6)-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that plays an important role in tumor resistance to alkylatin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Clin Oncol
Egile Nagusiak: Kurimoto, Tomoko, Kondo, Akihide, Ogino, Ikuko, Fujimura, Junya, Arakawa, Atsushi, Arai, Hajime, Shimizu, Toshiaki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: D.A. Spandidos 2017
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740829/
https://ncbi.nlm.nih.gov/pubmed/29285383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2017.1431
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